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MSCA – Postdoctoral Fellowship: Acute lymphoblastic… Job at HR – JOSEP CARRERAS LEUKAEMIA RESEARCH INSTITUTE – in Badalona, Barcelona provincia

Job Description

MSCA – Postdoctoral Fellowship: Acute lymphoblastic leukemia (ALL)


The Acute lymphoblastic leukemia (ALL) research group , led by Dr. Ribera of the Josep Carreras Leukaemia Research Institute ( Fundació Institut de Recerca Contra la Leucèmia Josep Carreras ) welcomes expressions of interest from excellent postdoctoral researchers to jointly apply to the European Commission Marie Sklodowska-Curie Postdoctoral Fellowship Scheme (MSCA-PF-2021).

We are a basic-translational research group working on adult T-cell Acute lymphoblastic leukemia (T-ALL). Two main research lines have been stablished in the laboratory:

i) Improvement of risk stratification of patients with adult T-ALL in the context of PETHEMA (Spanish program for hematological treatments) trials: we are using OMICs (SNPa; target deep sequencing [TDS] and digital karyotype [Bionanoenomics®]) to elucidate the mutational landscape of T-ALL patients included in the PETHEMA trials to refine their stratification and therefore improve their survival. The results obtained so far are currently being applied in the ALL-HR (Ph-) 2019 trial (NCT04179929). Research currently being conducted in the group will apply to future PETHEMA treatment protocols. This research line is currently financed by the national health system (ISCIII (PI19/01828).

ii) Development of new therapeutic alternatives to adult T-ALL patients: focused on the study of the mechanisms of relapse and the identification of the cells responsible for clonal resistance to treatment, we want to identify new ways to treat T-ALL patients to overcome resistance, which is responsible of treatment failure in 60% of T-ALL cases. In addition, we are using the genomic information obtained at time of diagnosis to explore new chemotherapeutic schedules in combination or not with new target therapies to improve treatment of these patients. For that, our lab has developed a primary co-culture system to grow leukemias in vitro and a PDX mouse model to assess these new anti-leukemic therapies in vivo .

Information regarding the Group Leader, composition of the research team, lines of research of the group and competitive funding can be found in our institutional website . The fellow would be co-supervised by Dr. Genescà .

The MSCA-PF grant provides living allowance covering one to two years’ salary, a mobility allowance and a family allowance (depending of the family status of the fellow), as well as research, training and networking costs, which translates in a very competitive salary conditions in relation to the average cost of living in Barcelona, which is a dynamic, vibrant and multi-cultural European capital city.

Applicants must have a strong publication record corresponding to their research experience (at least a first author publication in IF publication) and provide evidence of independence, a clear idea of what you will achieve during your fellowship and a reflexive understanding of your career development needs. Candidates will be expected to co-create their proposal with their host supervisor.

Enjoying a MSCA fellowship at IJC will allow you to gain research experience, develop research independence and maturity, improve your professional skills and make grow your international profile and network.

We are looking for ambitious, creative and scientifically curious experienced researchers of any nationality who meet the MSCA-PF eligibility criteria set by the call:

Be in the possession of a doctoral degree at the call deadline.

Comply with the mobility rule: you cannot apply for a fellowship in our institution if you have lived or carried out your main activity (work, studies, etc.) in Spain for more than 12 months in the 3 years before the call deadline (15/09/2021).

At the call deadline, researchers must have a maximum of 8 years full-time equivalent experience in research from the date that the researcher was in a possession of a doctoral degree. Years of experience outside research, research outside Europe for reintegrating researchers or career breaks (e.g. due to parental leave), will not be considered if a justification is provided.

Your Expression of Interest should include:
Your CV including a full list of your publications, research grants and projects and the contact details of 2 referees.

Motivation letter.

Deadline Expression of Interest: 15 June 2021 .

The candidates will be informed of the pre-selection results no more than two weeks after the expression of interest deadline.

Deadline MSCA-IF call: 15 September 2021 (tentative deadline).

The 2021 call is expected to open on late April and the call documents will be published on the Funding and Tenders Portal of the European Commission. You can find more information about MSCA-PF in the draft of the Horizon Europe Work Programme 2021-2022 / Annex 2. Marie Skłodowska-Curie actions .

About Company

Company: HR – JOSEP CARRERAS LEUKAEMIA RESEARCH INSTITUTE –

Company Location:  Badalona, Barcelona provincia

About HR - JOSEP CARRERAS LEUKAEMIA RESEARCH INSTITUTE -