Overview

Research Assistant Job at King’s College London in London

Job Description

Applications are invited for Research Assistant to work alongside with Dr Sherif Elsharkawy in the Faculty of Dentistry, Oral and Craniofacial Science at King’s College London. The research project will be focused on the design, synthesis and purification of recombinant mutated and non-mutated proteins, known to be involved in dental hard tissue development. These proteins will be employed to fabricate protein-based matrices to understand biomineralization mechanisms at multiple lengthscale. The goal will be to generate in vitro models to investigate developmental and pathological mineralisation. Alongside with the principal investigator, the candidate will play a major role in setting up a Biomineralization Lab at King’s College London.



Ideally, you will have (or near completion) a PhD in Chemistry, Materials Science, Molecular Biology, or Engineering and experience in biomineralization as well as one or more of the following areas:

1) Protein Production.

2) Protein-based mineralization.

3) Disordered proteins.

4) Hierarchical materials.

This post will be offered on a fixed-term contract for 12 months.

This is a full-time post.

The selection process will include a panel interview and a presentation.

For further information about the nature of the research, please find below key literature;

Elsharkawy, S. et al. Protein disorder-order interplay to guide the growth of hierarchical mineralized structures. Nature Communications 9, 2145 (2018).

Elsharkawy, S., Tejeda-Montes, E., Al-Jawad, M. & Mata, A. Preferential nucleation and crystal growth on microfabricated topography. Materials Today 19, 478-480 (2016).

Elsharkawy, S. & Mata, A. Hierarchical Biomineralization: from Nature’s Designs to Synthetic Materials for Regenerative Medicine and Dentistry. Advanced Healthcare Materials 7 (2018).

Ruan, Q. & Moradian-Oldak, J. Amelogenin and enamel biomimetics. Journal of Materials Chemistry B 3, 3112-3129 (2015).

Boskey, A. L. & Villarreal-Ramirez, E. Intrinsically disordered proteins and biomineralization. Matrix Biology 52-54, 43-59 (2016).

Informal enquiries should be emailed to Dr Sherif Elsharkawy at [email protected]

About Company

Company: King’s College London

Company Location:  London

About King's College London