Systems Engineer Jobs in Philadelphia, PA at Adaptimmune Therapeutics plc

Title: Systems Engineer

Company: Adaptimmune Therapeutics plc

Location: Philadelphia, PA

Salary: $150K – $200K*

Category: Pharmaceuticals & Biotech

Job Description


This hands-on role will design, implement and run infrastructure technologies in line with GxP requirements and execute associated IT services to deliver consistent, reliable and high-quality IT infrastructure availability and operations for Adaptimmune sites across the globe. Scope includes back end infrastructure systems and applications including but not limited to SCCM, on-premise Data Centers, Servers, Storage, Vulnerability Remediation, Disaster Recovery, and Voice and Data Networks, Connectivity, and Technical Support for Cloud Data Centers and Services.

The primary objective of the position is to be the subject matter expert for technology in scope, and execute efficient and effective operational IT process that adapt to the dynamics of the business. Deliver all operational services to meet expectations as measured by service level agreements, key performance indicators, and best practices in IT architecture, IT security, GxP compliance, and IT production operations support.


Implement and maintain the day to day operations of back end infrastructure including Cisco switches, Dell server, Ruckus wireless network, Fortinet Firewalls, Nimble Storage, and Avaya telephone systems.

Serve as the global SCCM subject matter expert and system owner for all system management responsibilities including, but not limited to, desktop imaging, application packaging and deployment, Windows and 3rd party patch management, software and hardware asset reporting, and related infrastructure upgrades.

Serve as the global operations lead for information security initiatives. Ensuring the integrity and protection of networks, systems, and applications by technical enforcement of organizational security policies, through server and workstation patch management, vulnerability remediation, anti-virus monitoring, and security infrastructure management.

For technologies in scope, actively monitor and take pro-active/preventative action on IT security, GxP and regulatory compliance. Identify and manage risk related to systems nearing end of life or maximum capacity.

Execute GxP and non-GxP change / release management processes. Execute disaster recovery and business continuity plans for technologies in scope.

Draft technical documentation for information technology systems and applications. Execute GXP documentation related to infrastructure systems where applicable.

Assist supervisor in planning for the infrastructure based on global business requirements, one IT function and IT strategies. Manages the benchmarking, analysis and recommendations for the improvement of the IT infrastructure and IT systems. Build business case and technology rationale for new systems.

Must be available to work off hours to support Manufacturing Operations (12pm-9pm, or 1pm-9pm)


10+ years in an IT function

6+ years managing IT infrastructure systems and applications

5+ years Active Directory, Group policy administration

5+ years VMware experience

5+ years storage administration

5+ years SCCM administration

4+ years information security systems administration

4+ years supporting infrastructure systems hosting GXP applications

Bachelor’s degree in Computer Science, Engineering or equivalent experience

Strong ability to collaborate with various IT roles across the globe

Must be able to operate in a global operation and support environment



About Adaptimmune Therapeutics plc